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HAFILLER Sodium Hyaluronate Injections

HAFILLER sodium hyaluronate injections are a series of dermal filler products researched and developed by Jingjia Medical. After years of dedicated research and development, Jingjia Medical have successfully extracted sodium hyaluronic from chicken combs which is the main material to produce sodium hyaluronic acid injection. HAFILLER provides you medical-grade sodium hyaluronate injection with high bio-compatibility and few side effects, which make it ideal for arthritis treatment, ophthalmic surgery aid and cosmetic surgery.

Functions of Sodium Hyaluronate Acid Injection

Hyaluronic acid (HA) is a naturally occurring substance found in the body's connective tissues, skin, and synovial fluid in joints. Sodium Hyaluronic Acid Injection has the following effects in different parts of body.

    • Sodium hyaluronate acid injection usedas dermal filler helps attract and retain moisture in the skin, providing deep hydration. That benefits skin elasticity and suppleness.
    • HA injectionadds volume to the skin, filling in wrinkles, fine lines, and areas of lost volume (e.g., cheeks, lips, forehead, breast)
    • HA injection improves overall skin texture and elasticity by promoting collagen synthesis.
    • Sodium hyaluronate injectioncan accelerate the healing process of skin wounds and scars by promoting tissue regeneration and reducing inflammation. They also help in the formation of new blood vessels, enhancing nutrient supply to the affected area.
    • Sodium hyaluronate acid injectionsupport the repair and regeneration of connective tissues, facilitating cell migration and proliferation. They help rebuild the extracellular matrix, providing structural support to tissues.
    • In connective tissues, HA injections improve hydration and lubrication, which is essential for tissue flexibility and resilience.It also helps in maintaining the function integrity.
    • HA has anti-inflammatory properties, and its injections can help alleviate pain and swelling associated with conditions like tendonitis or other inflammatory disorders.
    • During cataract surgery, HA injections help maintain the depth and stability of the anterior chamber of the eye, and providespace for the surgeon to work, which is essential for preventing the collapse of the chamber and ensuring a clear surgical field.
    • Sodium hyaluronate gel injectionfacilitates the separation of tissues, such as the lens capsule from the lens itself, which is vital during lens implantation and other intraocular procedures.
    • In ophthalmic surgery, Sodium hyaluronate gel injectioncreates a protective barrier over the corneal endothelium (the innermost layer of the cornea). This protection is crucial to prevent damage to these cells from surgical instruments and ultrasonic energy during phacoemulsification (a technique used to emulsify and remove the lens).

Safety and Performance of HAFILLER Sodium Hyaluronic Acid Injection

High Safety

The safety of sodium hyaluronate injection is a major concern for consumers and medical professionals. Jingjia Medical is one of the few factories in the world that can produce injection-grade hyaluronic acid and has the largest production base of hyaluronic acid raw materials in the world. The production process strictly follows the GMP and ISO standards. All production equipment adopts an advanced automation system to reduce man-made operational risk and ensure product consistency and safety. The workshop is dust-free and sterile. Persons and items entering the production area undergo strict disinfection and decontamination treatment. From the procurement of raw materials to the packaging of the final product, every link goes through multiple quality tests.With a number of clinical trials and doctor's feedback, it showed that Aquaderm cross-linked dermal filler has been recognized by global customers. Besides, we will provide continuous clinical safety data support for global patients through a large number of clinical follow-ups every year.

Remarkable Products Performance

We select high-purity sodium hyaluronate raw materials and employ proprietary technology and purification techniques to remove impurities and retain active ingredients. This enhances the purity and quality of our products, ensuring they possess superior biocompatibility and stability, keeping our products at the forefront of the market.HAFILLER’ s extrusion force curve is smoother than the Swedish brands, doctors will have a better injection experience with HAFILLER, easier to use and smoother. HAFILLER’ s enzymolysis in vitro time is less than the Swedish brands. These show that HAFILLER sodium hyaluronate injections have longer-lasting results.

What is Cross-linked Hyaluronate Acid ? 

Hyaluronic acid is widely used in reconstructive surgery, eye surgery, or as a cosmetic product to fill wrinkles due to its excellent biocompatibility and physicochemical properties. However, hyaluronic acid is rapidly degraded in the body by enzymatic action and has a short retention time in the body. Frequent repeated injections are needed to maintain the effect.

Cross-linking agents turn hyaluronic acid into a gelatinous cross-linked hyaluronic acid, which on one hand enhances its physical viscoelasticity and on the other hand increases its stability and slows down the degradation rate. This effectively compensates for the short retention time of sodium hyaluronate in tissues while still maintaining good biocompatibility and viscoelasticity.

In youthful skin, fibroblasts are polygonal and can secrete large amounts of collagen and elastin. Whereas, in aging skin, collagen fibers tear, losing their support and traction functions. And  fibroblasts collapse into a round structure, reducing their synthetic capability. They also synthesize metalloproteinases, which further damage already compromised collagen fibers. The primary role of dermal filler of cross-linked hyaluronic acid is to improve skin texture by promoting the traction of collagen fibers on fibroblasts, activating fibroblasts to synthesize new collagen.

China Cross-linked Dermal Filler Manufacture Jingjia Medical

To be a reliable dermal filler manufacture with technological strength, Jingjia Medical made efforts. In November 2014, Jingjia Medical formally established a medical sodium hyaluronate cross-linking technology research and development center. Since then, Jingjia Medical speed up the investment in research and development funds, the purchase of equipment and the introduction of research and development talents. In June 2016, the R&D center was awarded the Hangzhou “Medical Sodium Hyaluronate Cross-linking Timely R&D Center”. In November 2018, Jingjia Medical was awarded the Zhejiang Province “Sodium Hyaluronate Cross linking Technology Provincial High-tech Enterprise Research and Development Center”. These achievements make the foundation for Jingjia Medical being a reliable cross-linked dermal filler supplier.

Advantages of Jingjia Dermal Filler Injection Manufacturer

  • Advanced Cross-linking technology

This technology uses cross-linking agent to transform hyaluronic acid into a stable polymer gel with three-dimensional structure, enhances the longevity and effectiveness of the dermal filler products. The cross-linked hyaluronic acid is resistant to enzymatic degradation, providing longer-lasting results compared to non-cross-linked fillers.

  • Performance hyaluronic acid dermal filler products

Jingjia Medical now is a leading hyaluronic acid dermal filler manufacturer in China. Supported by advanced cross-linking technology, Jingjia Medical is able to provide performance hyaluronic acid dermal filler products and evolutionary approach to natural and long-lasting medical aesthetic Effects.

  • Versatile treatment range

For different treatment ranges and different treatment purposes, Jingjia Medical as a professional dermal filler supplier, has targeted cosmetic medicine products. 

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Zhejiang Jingjia Medical Technology Co., Ltd. was established in July 1995. It is a national high-tech enterprise integrating R&D, manufacturing and sales of biomedical materials.

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